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MedChemExpress
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TargetMol
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Sanofi
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Alsachim SAS
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MSN Laboratories
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MSN Laboratories
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Charles River Laboratories
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Toronto Research Chemicals
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China Pharmaceuticals Inc
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Ranbaxy Laboratories
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Image Search Results
Journal: The Korean Journal of Pain
Article Title: Pharmacological interactions between intrathecal pregabalin plus tianeptine or clopidogrel in a rat model of neuropathic pain
doi: 10.3344/kjp.2022.35.1.59
Figure Lengend Snippet: Time course curves of intrathecal pregabalin (A), tianeptine (B) and clopidogrel (C) on the hind paw withdrawal response after spinal nerve ligation. Data are presented as the withdrawal threshold (g). Each line represents the means ± standard error of the mean of 6 rats.
Article Snippet: Co., Ltd., Seoul, Korea), and
Techniques: Ligation
Journal: The Korean Journal of Pain
Article Title: Pharmacological interactions between intrathecal pregabalin plus tianeptine or clopidogrel in a rat model of neuropathic pain
doi: 10.3344/kjp.2022.35.1.59
Figure Lengend Snippet: Dose response effect of intrathecal pregabalin, tianeptine and clopidogrel (A), or mixture of pregabalin and tianeptine (B) on the hind paw withdrawal response after spinal nerve ligation. Data are presented as the percent of maximal possible effect (% MPE). Each line represents the means ± standard error of the mean of 6 rats. P: pregabalin ED 50 , T: tianeptine ED 50 , ED 50 : 50% effective dose. * P < 0.05, *** P < 0.001, compared with vehicle.
Article Snippet: Co., Ltd., Seoul, Korea), and
Techniques: Ligation
Journal: The Korean Journal of Pain
Article Title: Pharmacological interactions between intrathecal pregabalin plus tianeptine or clopidogrel in a rat model of neuropathic pain
doi: 10.3344/kjp.2022.35.1.59
Figure Lengend Snippet: A fixed dose analysis for the interaction between intrathecal clopidogrel (300 μg) and pregabalin. Data are presented as the percent of maximal possible effect (% MPE). Each line represents the means ± standard error of the mean of 6 rats.
Article Snippet: Co., Ltd., Seoul, Korea), and
Techniques:
Journal: Research and Practice in Thrombosis and Haemostasis
Article Title: Impact of age on in vitro metabolism of clopidogrel: a potential explanation for high on-treatment platelet reactivity in the elderly?
doi: 10.1016/j.rpth.2022.100014
Figure Lengend Snippet: Concentrations of clopidogrel-active metabolite after metabolism by <70 (young) and ≥70 (old) years old human liver microsomes after 30 minutes (T30) or 45 minutes (T45) of incubation. n = 21 in each group. ∗∗: P < .01 ∗∗∗: P < .001. HLM,
Article Snippet:
Techniques: Incubation
Journal: Research and Practice in Thrombosis and Haemostasis
Article Title: Impact of age on in vitro metabolism of clopidogrel: a potential explanation for high on-treatment platelet reactivity in the elderly?
doi: 10.1016/j.rpth.2022.100014
Figure Lengend Snippet: Area under the curve and maximal aggregation inhibition of platelet aggregation after 30 (T30) and 45 (T45) minutes of incubation of clopidogrel with either old or young human liver microsomes.
Article Snippet:
Techniques: Inhibition, Incubation, Indirect Immunoperoxidase Assay
Journal: Research and Practice in Thrombosis and Haemostasis
Article Title: Impact of age on in vitro metabolism of clopidogrel: a potential explanation for high on-treatment platelet reactivity in the elderly?
doi: 10.1016/j.rpth.2022.100014
Figure Lengend Snippet: Relationship between concentration of clopidogrel-active metabolite (μg/L) and inhibition of platelet aggregation (IPA). AUC-IPA with old HLMs (A), AUC-IPA with young HLMs (B), maximal aggregation-IPA with old HLMs (C), and maximal aggregation-IPA with young HLMs (D). Light red or blue squares stand for T30 incubation ( n = 8), and dark red and blue squares stand for T45 incubation ( n = 13). AUC, area under the curve; clopidogrel-AM, clopidogrel-active metabolite; HLMs, human liver microsomes; IPA, inhibition of platelet aggregation.
Article Snippet:
Techniques: Concentration Assay, Inhibition, Incubation